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Особую группу составляли больные параноидной шизофренией, которым алпразолам назначался в до­полнение к нейролептикам (клозапин, оланзапин, палиперидон, рисперидон) в качестве противотревожного средства и потенцирующего седативный эффект. Это позволяло снизить дозы антипсихотиков, что особенно важно при проведении лечения в амбулаторных усло­виях в целях улучшения социальной адаптации и качес­тва жизни.

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